tips on baby, equipment for babies, games for babies, health care for babies.
Saturday, October 2, 2010
Healthtips-How HRT and the Pill can lead to breast cance
And now medicalresearchers at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences in Vienna have identified a key mechanism that allows these synthetic sex hormones to directly affect mammary cells.
The research team shows that a synthetic female sex hormone used in HRT and contraceptive pills can trigger RANKL, the master regulator of healthy bones, in breast cells of mice. As a consequence, these mammary cells start to divide and multiply and fail to die when they should. Moreover, stem cells in the breast become able to renew themselves, ultimately resulting in breast cancer.
In a different set of mouse treatment tests, researchers at Amgen have found that pharmacologic blocking of the RANKL system significantly delays mammary tumor formation leading to significantly fewer breast cancers in mice. In another mouse model, RANKL inhibition not only decreased breast tumor formation but also reduced lung metastasis.
"I have to admit it completely surprised me just how massive the effects of the system were. Millions of women take progesterone derivatives in contraceptives and for hormonal replacement therapy. Since our results show that the RANKL system is an important molecular link between a synthetic sex hormone and breast tumors, one day women may be able to reduce their risk by taking blocking medicines in advance to prevent breast cancer," Nature quoted Prof Josef Penninger as saying.
A monoclonal antibody, denosumab, that blocks RANKL has been recently approved in the US and the EU for the treatment of osteoporosis, and is currently under review for the treatment of bone metastases in patients with advanced cancer.
This scientific article has been published on Nature's website.
The research team shows that a synthetic female sex hormone used in HRT and contraceptive pills can trigger RANKL, the master regulator of healthy bones, in breast cells of mice. As a consequence, these mammary cells start to divide and multiply and fail to die when they should. Moreover, stem cells in the breast become able to renew themselves, ultimately resulting in breast cancer.
In a different set of mouse treatment tests, researchers at Amgen have found that pharmacologic blocking of the RANKL system significantly delays mammary tumor formation leading to significantly fewer breast cancers in mice. In another mouse model, RANKL inhibition not only decreased breast tumor formation but also reduced lung metastasis.
"I have to admit it completely surprised me just how massive the effects of the system were. Millions of women take progesterone derivatives in contraceptives and for hormonal replacement therapy. Since our results show that the RANKL system is an important molecular link between a synthetic sex hormone and breast tumors, one day women may be able to reduce their risk by taking blocking medicines in advance to prevent breast cancer," Nature quoted Prof Josef Penninger as saying.
A monoclonal antibody, denosumab, that blocks RANKL has been recently approved in the US and the EU for the treatment of osteoporosis, and is currently under review for the treatment of bone metastases in patients with advanced cancer.
This scientific article has been published on Nature's website.
--ANI
Posted by
sri sultan hamengkubuwono[
BABY FOOD RECIPES
BABY FOOD RECIPES - CHICKEN HEARTS APPLE
Baby food recipes
Material:
250 grams of chicken liver
2 apples, peeled, seeded, chopped
1 carrot, peeled and cut into pieces
3 pieces potatoes, peeled and cut into pieces
2 stalks celery, chopped
3 tablespoons green peas
Directions:
1. Cook all ingredients until cooked.
2. Drain and puree (or chopped finely for children ages 8 months and up)
BABY FOOD RECIPES - FISH APPLE
Baby food recipes
Material:
2 pieces of fish fillets
2 apples, peeled, cut into pieces
Directions:
1. Boil the ingredients until cooked. Drain and puree.
Note:
For children 8 months, the food should not be crushed but only finely chopped. It is good to stimulate the growth of teeth and to train the muscles of the mouth and gums to bite.
BABY FOOD RECIPES - CARAPPEAR
Baby food recipes
Material:
2 stalks carrots, peeled, cut into pieces
2 apples, peeled, cut into pieces
2 pieces of pear, peeled and cut into pieces
Directions:
1. Kl Boil carrots for 10 minutes, then amsukkan apple and pear. Cook until soft.
2. Drain and puree (or chopped finely for children ages 8 months and up)
BABY FOOD RECIPES - steamed fish
Baby food recipes
Material:
1 snapper fillet (or other fish species, according to taste)
Directions:
1. Steam the fish until cooked and then mashed.
2. Can be mixed with pureed vegetables (carrots, broccoli, etc.).
BABY FOOD RECIPES - Broccoli POTATO
Baby food recipes
Material:
7 broccoli florets, discarding the stem
2 potatoes, peeled, cut into pieces
Chicken broth / meat taste (only boiled water chicken / meat, without salt or other seasonings)
Directions:
1. Steam the broccoli and potatoes until cooked.
2. Blend the two ingredients with the processor / blender.
3. Give the broth to taste.
BABY FOOD RECIPES - VEGETABLE INTERFERENCE
Baby food recipes
Material:
1 carrot, peeled, cut into pieces
1 piece of potato, peeled, cut into pieces
2 tablespoons green peas (can be replaced other green vegetables, eg broccoli,
zuchini, celery, etc.)
Chicken broth / meat taste (only boiled water chicken / meat, without garammaupun other seasonings)
Directions:
1. Boiled / steamed until cooked all the ingredients and puree.
2. Give the chicken broth / meat taste.
BABY FOOD RECIPES - CHICKEN SOUP
Baby food recipes
Material:
1 piece of chicken thighs, remove skin, cut meat into pieces (bones were not removed)
1 stalk celery, chopped
2 potatoes, peeled, cut into pieces
1 stick carrot, peeled, cut into pieces
2 tablespoons green peas
500 ml water
Directions:
1. Cook all ingredients until cooked.
2. Discard the chicken bones, then puree all ingredients
BABY FOOD RECIPES - puree CARROT
Baby food recipes
Material:
2 medium carrots, peeled
Boiled water to taste
Directions:
1. Steam the carrots until tender then puree. Add water as needed.
2. Presentation: Give the carrot puree as single or mixed foods
with pulp POTATO / SWEET POTATOES porridge.
BABY FOOD RECIPES - pea puree
Baby food recipes
Material:
250 grams of fresh or frozen peas
Directions:
1. Boil peas until cooked and then mashed.
2. Strain the rough skin so do not take part inedible.
3. Presentation: Give peas puree as a single food or
mixed with porridge POTATO / SWEET POTATOES porridge.
Baby food recipes
Material:
250 grams of chicken liver
2 apples, peeled, seeded, chopped
1 carrot, peeled and cut into pieces
3 pieces potatoes, peeled and cut into pieces
2 stalks celery, chopped
3 tablespoons green peas
Directions:
1. Cook all ingredients until cooked.
2. Drain and puree (or chopped finely for children ages 8 months and up)
BABY FOOD RECIPES - FISH APPLE
Baby food recipes
Material:
2 pieces of fish fillets
2 apples, peeled, cut into pieces
Directions:
1. Boil the ingredients until cooked. Drain and puree.
Note:
For children 8 months, the food should not be crushed but only finely chopped. It is good to stimulate the growth of teeth and to train the muscles of the mouth and gums to bite.
BABY FOOD RECIPES - CARAPPEAR
Baby food recipes
Material:
2 stalks carrots, peeled, cut into pieces
2 apples, peeled, cut into pieces
2 pieces of pear, peeled and cut into pieces
Directions:
1. Kl Boil carrots for 10 minutes, then amsukkan apple and pear. Cook until soft.
2. Drain and puree (or chopped finely for children ages 8 months and up)
BABY FOOD RECIPES - steamed fish
Baby food recipes
Material:
1 snapper fillet (or other fish species, according to taste)
Directions:
1. Steam the fish until cooked and then mashed.
2. Can be mixed with pureed vegetables (carrots, broccoli, etc.).
BABY FOOD RECIPES - Broccoli POTATO
Baby food recipes
Material:
7 broccoli florets, discarding the stem
2 potatoes, peeled, cut into pieces
Chicken broth / meat taste (only boiled water chicken / meat, without salt or other seasonings)
Directions:
1. Steam the broccoli and potatoes until cooked.
2. Blend the two ingredients with the processor / blender.
3. Give the broth to taste.
BABY FOOD RECIPES - VEGETABLE INTERFERENCE
Baby food recipes
Material:
1 carrot, peeled, cut into pieces
1 piece of potato, peeled, cut into pieces
2 tablespoons green peas (can be replaced other green vegetables, eg broccoli,
zuchini, celery, etc.)
Chicken broth / meat taste (only boiled water chicken / meat, without garammaupun other seasonings)
Directions:
1. Boiled / steamed until cooked all the ingredients and puree.
2. Give the chicken broth / meat taste.
BABY FOOD RECIPES - CHICKEN SOUP
Baby food recipes
Material:
1 piece of chicken thighs, remove skin, cut meat into pieces (bones were not removed)
1 stalk celery, chopped
2 potatoes, peeled, cut into pieces
1 stick carrot, peeled, cut into pieces
2 tablespoons green peas
500 ml water
Directions:
1. Cook all ingredients until cooked.
2. Discard the chicken bones, then puree all ingredients
BABY FOOD RECIPES - puree CARROT
Baby food recipes
Material:
2 medium carrots, peeled
Boiled water to taste
Directions:
1. Steam the carrots until tender then puree. Add water as needed.
2. Presentation: Give the carrot puree as single or mixed foods
with pulp POTATO / SWEET POTATOES porridge.
BABY FOOD RECIPES - pea puree
Baby food recipes
Material:
250 grams of fresh or frozen peas
Directions:
1. Boil peas until cooked and then mashed.
2. Strain the rough skin so do not take part inedible.
3. Presentation: Give peas puree as a single food or
mixed with porridge POTATO / SWEET POTATOES porridge.